BS7841

PCGF6 antibody from Bioworld Technology, Inc
MBLR, RNF134
Western blot
Data presented on provider website
Immunocytochemistry
Data presented on provider website

Antibody data

Product number
BS7841
Provider
Bioworld Technology, Inc
Product name
PCGF6 polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS7841
Antibody type
Polyclonal
Antigen
Recombinant full length Human PCGF6.
Description
Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. Several members of the PcG contain ring finger domains and are identified as a subclass of RING finger proteins. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain the RING-type zinc finger conserved domain are generally involved in the ubiquitination pathway of protein degradation. PCGF6 (polycomb group ring finger 6), also known as MBLR or RNF134, is a 350 amino acid nuclear protein that is ubiquitously expressed and contains one RING-type zinc finger. PCGF6 acts as a transcriptional repressor and regulates the level of histone H3K4Me3 by activating SmcY histone demethylase. PCGF6 exists as two alternatively spliced isoforms.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.