PLA2G4C

This gene encodes a protein which is a member of the phospholipase A2 enzyme family which hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids, both of which serve as precursors in the production of signaling molecules. The encoded protein has been shown to be a calcium-independent and membrane bound enzyme. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]

Description

Phospholipase A2 group IVC

Tissue specificity

Tissue enhanced (retina, skeletal muscle)

Subcell location

Cytosol

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
RAS pathway related proteins

Chromosome

19 (48047843 - 48110817)

Ensembl ID

ENSG00000105499  (ver. 103.38)

Orthologs

Mouse Pla2g4c: ENSMUSG00000033847

UniProt

Q9UP65

neXtProt

NX_Q9UP65

Human splice variants
Mouse splice variants

Protein structure