Tissue expression
Cell line expression
Protein structure
SESN3
Sestrin 3MGC29667, SEST3
This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Top validated antibodies |
|||||
Novus Biologicals | NBP1-31702 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
Proteintech Group | 11431-2-AP | 10 references | Polyclonal |
WB
EL |
|
antibodies-online | ABIN2845697 | 2 references | Polyclonal |
WB
IHC |
|
Bioss | bs-6100R | 1 references | Polyclonal |
WB
EL
ICC
IHC |
|
LSBio | LS-B14182 | Polyclonal |
WB
ICC
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider