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- Product number
- ABIN394131 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Inhibitor of Growth Family, Member 3 (ING3) (AA 1-93) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human, Rat
- Host
- Mouse
- Epitope
- AA 1-93
- Isotype
- IgG
- Antibody clone number
- 2C4
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.
The tumor suppressor ING3 is degraded by SCF(Skp2)-mediated ubiquitin-proteasome system.
Downregulation of ING3 mRNA expression predicts poor prognosis in head and neck cancer.
Prognostic significance of nuclear ING3 expression in human cutaneous melanoma.
ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression.
Maestrini E, Pagnamenta AT, Lamb JA, Bacchelli E, Sykes NH, Sousa I, Toma C, Barnby G, Butler H, Winchester L, Scerri TS, Minopoli F, Reichert J, Cai G, Buxbaum JD, Korvatska O, Schellenberg GD, Dawson G, de Bildt A, Minderaa RB, Mulder EJ, Morris AP, Bailey AJ, Monaco AP, IMGSAC.
Molecular psychiatry 2010 Sep;15(9):954-68
Molecular psychiatry 2010 Sep;15(9):954-68
The tumor suppressor ING3 is degraded by SCF(Skp2)-mediated ubiquitin-proteasome system.
Chen G, Wang Y, Garate M, Zhou J, Li G
Oncogene 2010 Mar 11;29(10):1498-508
Oncogene 2010 Mar 11;29(10):1498-508
Downregulation of ING3 mRNA expression predicts poor prognosis in head and neck cancer.
Gunduz M, Beder LB, Gunduz E, Nagatsuka H, Fukushima K, Pehlivan D, Cetin E, Yamanaka N, Nishizaki K, Shimizu K, Nagai N
Cancer science 2008 Mar;99(3):531-8
Cancer science 2008 Mar;99(3):531-8
Prognostic significance of nuclear ING3 expression in human cutaneous melanoma.
Wang Y, Dai DL, Martinka M, Li G
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Jul 15;13(14):4111-6
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Jul 15;13(14):4111-6
ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression.
Shi X, Hong T, Walter KL, Ewalt M, Michishita E, Hung T, Carney D, Peña P, Lan F, Kaadige MR, Lacoste N, Cayrou C, Davrazou F, Saha A, Cairns BR, Ayer DE, Kutateladze TG, Shi Y, Côté J, Chua KF, Gozani O
Nature 2006 Jul 6;442(7098):96-9
Nature 2006 Jul 6;442(7098):96-9
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