ABCB9

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This family member functions in the translocation of peptides from the cytosol into the lysosomal lumen. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specificities. [provided by RefSeq, Jul 2011]

Description

ATP binding cassette subfamily B member 9

Tissue specificity

Tissue enhanced (brain, testis)

Subcell location

Vesicles

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Kim et al 2014)
Transporters

Chromosome

12 (122920951 - 122981649)

Ensembl ID

ENSG00000150967  (ver. 103.38)

Orthologs

Mouse Abcb9: ENSMUSG00000029408

UniProt

Q9NP78

neXtProt

NX_Q9NP78

Human splice variants
Mouse splice variants

Protein structure