SURF4

This gene is located in the surfeit gene cluster, which is comprised of very tightly linked housekeeping genes that do not share sequence similarity. The encoded protein is a conserved integral membrane protein that interacts with endoplasmic reticulum-Golgi intermediate compartment proteins. Disruption of this gene results in reduced numbers of endoplasmic reticulum-Golgi intermediate compartment clusters and redistribution of coat protein I to the cytosol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Description

Surfeit 4

Tissue specificity

Low tissue specificity

Subcell location

Nuclear membrane, Endoplasmic reticulum, Golgi apparatus, Cytosol

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transporters

Chromosome

9 (133361450 - 133376166)

Ensembl ID

ENSG00000148248  (ver. 103.38)

Orthologs

Mouse Surf4: ENSMUSG00000014867

UniProt

O15260

neXtProt

NX_O15260

Human splice variants
Mouse splice variants

Protein structure