BS6551

antibody from Bioworld Technology, Inc
Targeting: SCARB1 CD36L1, CLA-1, CLA1, SR-BI, SRB1
Provider product page for BS6551
Western blot
Immunohistochemistry

Antibody data

Product number
BS6551 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SCARB1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human SCARB1.
Description
The macrophage class A scavenger receptors (SR-A) type I and II mediate the uptake of modified low density lipoprotein (LDL), while the scavenger receptor class B type 1 (SR-B1) mediates the selective uptake of cholesterol and cholesterol esters (CE) from HDLs into cells. SREC, Ox-LDL-R1, SR-A and SR-B1 may all be involved in the early development of atherosclerosis. SR-B1, an integral membrane protein, acts as a receptor for various ligands, including apoptotic cells, cholesterol ester, phospholipids, lipoproteins and phosphatidyl-serine. SR-B1, which may be involved in phagocytosis of apoptotic cells, enables the movement of cholesterol between the cell surface and extracellular donors and acceptors. Although it is widely expressed, SR-B1 localizes primarily to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SCARB1 protein structure - BS6551 shown in red.