PDZRN3

This gene encodes a member of the LNX (Ligand of Numb Protein-X) family of RING-type ubiquitin E3 ligases. This protein may function in vascular morphogenesis and the differentiation of adipocytes, osteoblasts and myoblasts. This protein may be targeted for degradation by the human papilloma virus E6 protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Description

PDZ domain containing ring finger 3

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

3 (73382431 - 73624941)

Ensembl ID

ENSG00000121440  (ver. 103.38)

Orthologs

Mouse Pdzrn3: ENSMUSG00000035357

UniProt

Q9UPQ7

neXtProt

NX_Q9UPQ7

Human splice variants
Mouse splice variants

Protein structure