SLC25A21

SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA. [supplied by OMIM, Apr 2004]

Description

solute carrier family 25 member 21

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas), Transporters

Chromosome

14:q13.3 (36677921 - 37172606)

Ensembl ID

ENSG00000183032  (ver. 99.38)

Orthologs

Mouse Slc25a21: ENSMUSG00000035472

UniProt

Q9BQT8

neXtProt

NX_Q9BQT8

Human splice variants
Mouse splice variants