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Protein structure
POLR2A
RNA polymerase II subunit APOLR2, POLRA, RPB1
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  MA1-46093 |
6 references | Monoclonal |
WB
ICC
IHC
ChIP
OA
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| Novus Biologicals | NB200-598 |
9 references | Monoclonal |
WB
EL
ICC
IP
FC
ChIP
|
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| antibodies-online | ABIN268311 |
6 references | Monoclonal |
WB
EL
ICC
IP
FC
ChIP
|
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| GeneTex | GTX80341 |
1 references | Monoclonal |
WB
EL
ICC
IP
ChIP
|
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| NSJ Bioreagents | RQ5679 |
Polyclonal |
WB
EL
ICC
IHC
FC
|
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