HIVEP3

This gene encodes a member of the human immunodeficiency virus type 1 enhancer-binding protein family. Members of this protein family contain multiple zinc finger and acid-rich (ZAS) domains and serine-threonine rich regions. This protein acts as a transcription factor and is able to regulate nuclear factor kappaB-mediated transcription by binding the kappaB motif in target genes. This protein also binds the recombination signal sequence that flanks the V, D, and J regions of immunoglobulin and T-cell receptors. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Sep 2011]

Description

HIVEP zinc finger 3

Tissue specificity

Tissue enhanced (lymphoid tissue)

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transcription factors

Chromosome

1 (41506365 - 42035925)

Ensembl ID

ENSG00000127124  (ver. 103.38)

Orthologs

Mouse Hivep3: ENSMUSG00000028634

UniProt

Q5T1R4

neXtProt

NX_Q5T1R4

Human splice variants
Mouse splice variants

Protein structure