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Protein structure
GLRX
GlutaredoxinGRX, GRX1
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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| Proteintech Group |  15804-1-AP |
3 references | Polyclonal |
WB
EL
ICC
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| GeneTex | GTX54140 |
1 references | Polyclonal |
WB
ICC
IHC
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| antibodies-online | ABIN1876503 |
Polyclonal |
WB
ICC
IHC
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| Acris Antibodies GmbH | AM31076PU-N |
Monoclonal |
WB
EL
IHC
|
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| Abnova Corporation | H00002745-M02 |
Monoclonal |
WB
EL
IHC
|
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