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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- V2086 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- p27Kip1 Antibody
- Antibody type
- Monoclonal
- Antigen
- Purified GST-p27 fusion protein of human origin was used as the immunogen for this p27Kip1 antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- SX53G8
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the p27Kip1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references In vitro and in vivo activity of a novel locked nucleic acid (LNA)-inhibitor-miR-221 against multiple myeloma cells.
Prospective evaluation of a preoperative biomarker panel for prediction of upstaging at radical cystectomy.
Antitumoral activity of lenalidomide in in vitro and in vivo models of mantle cell lymphoma involves the destabilization of cyclin D1/p27KIP1 complexes.
p27 and BCL2 expression predicts response to chemotherapy in head and neck squamous cell carcinomas.
Placental estrogen suppresses cyclin D1 expression in the nonhuman primate fetal adrenal cortex.
p27 expression in post-treatment rectal cancer: a potential novel approach for predicting residual nodal disease.
A heterozygous frameshift mutation in exon 1 of CDKN1B gene in a patient affected by MEN4 syndrome.
Di Martino MT, Gullà A, Gallo Cantafio ME, Altomare E, Amodio N, Leone E, Morelli E, Lio SG, Caracciolo D, Rossi M, Frandsen NM, Tagliaferri P, Tassone P
PloS one 2014;9(2):e89659
PloS one 2014;9(2):e89659
Prospective evaluation of a preoperative biomarker panel for prediction of upstaging at radical cystectomy.
Shariat SF, Passoni N, Bagrodia A, Rachakonda V, Xylinas E, Robinson B, Kapur P, Sagalowsky AI, Lotan Y
BJU international 2014 Jan;113(1):70-6
BJU international 2014 Jan;113(1):70-6
Antitumoral activity of lenalidomide in in vitro and in vivo models of mantle cell lymphoma involves the destabilization of cyclin D1/p27KIP1 complexes.
Moros A, Bustany S, Cahu J, Saborit-Villarroya I, Martínez A, Colomer D, Sola B, Roué G
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Jan 15;20(2):393-403
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Jan 15;20(2):393-403
p27 and BCL2 expression predicts response to chemotherapy in head and neck squamous cell carcinomas.
Moreno-Galindo C, Hermsen M, García-Pedrero JM, Fresno MF, Suárez C, Rodrigo JP
Oral oncology 2014 Feb;50(2):128-34
Oral oncology 2014 Feb;50(2):128-34
Placental estrogen suppresses cyclin D1 expression in the nonhuman primate fetal adrenal cortex.
Dumitrescu A, Aberdeen GW, Pepe GJ, Albrecht ED
Endocrinology 2014 Dec;155(12):4774-84
Endocrinology 2014 Dec;155(12):4774-84
p27 expression in post-treatment rectal cancer: a potential novel approach for predicting residual nodal disease.
Leibold T, Hui VW, Shia J, Ruby JA, Riedel ER, Guillem JG
American journal of surgery 2014 Aug;208(2):228-34
American journal of surgery 2014 Aug;208(2):228-34
A heterozygous frameshift mutation in exon 1 of CDKN1B gene in a patient affected by MEN4 syndrome.
Tonelli F, Giudici F, Giusti F, Marini F, Cianferotti L, Nesi G, Brandi ML
European journal of endocrinology / European Federation of Endocrine Societies 2014 Aug;171(2):K7-K17
European journal of endocrinology / European Federation of Endocrine Societies 2014 Aug;171(2):K7-K17
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of human colon stained with p27Kip1 antibody.
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of FFPE prostate carcinoma with p27Kip1 antibody
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- FACS: Intracellular flow testing of HeLa cells with Alexa Fluor 488 conjugated p27Kip1 antibody (green) and isotype control (gray).
