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Protein structure
KIRREL3
Kirre like nephrin family adhesion molecule 3KIAA1867, KIRRE, NEPH2
The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. The protein encoded by this gene is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
Top validated antibodies |
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| GeneTex |  GTX32140 |
Polyclonal |
WB
EL
ICC
IHC
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| Boster Biological Technology | A07202 |
Polyclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | PA5-72824 |
Polyclonal |
WB
EL
ICC
IHC
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| OriGene | TA349103 |
Polyclonal |
WB
ICC
IHC
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| Antibodies Incorporated / NeuroMab | 73-282 |
Monoclonal |
WB
ICC
IHC
|
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