APLP2

gene product
APPH, APPL2
This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
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Novus Biologicals
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Proteintech Group
1 antibody
antibodies-online
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Biorbyt
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NovoPro Bioscience Inc.
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OriGene
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Atlas Antibodies
1 antibody
LifeSpan BioSciences, Inc.
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Boster Biological Technology
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Aviva Systems Biology
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Abnova Corporation
4 antibodies
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3 antibodies
R&D Systems
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Abgent
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Invitrogen Antibodies
5 antibodies
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Affinity Biosciences
1 antibody
HUABIO Research
1 antibody
Abbkine Scientific Co.Ltd.
3 antibodies
SignalChem
1 antibody
Acris Antibodies GmbH
3 antibodies
NSJ Bioreagents
2 antibodies
Creative Diagnostics
4 antibodies
United States Biological
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MyBioSource
8 antibodies
St John's Laboratory
4 antibodies
Abbexa
11 antibodies
RabMAbs
2 antibodies
Creative Biolabs
5 antibodies
Leading Biology
2 antibodies
Sigma-Aldrich
1 antibody