Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APR03179G - Provider product page
- Provider
- Leading Biology
- Product name
- RANBP2 / TRP1 Antibody (aa1050-1100)
- Antibody type
- Polyclonal
- Description
- E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Binds single- stranded RNA (in vitro). May bind DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB.
- Reactivity
- Human, Mouse, Rat, Bovine
- Host
- Rabbit
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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