Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60276 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- ZNF9 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human ZNF9.
- Description
- Cellular nucleic acid binding protein (CNBP) is a highly conserved RNA-binding protein that plays a fundamental biological role in eukaryotic cells by increasing heterologous protein production. CNBP localizes to the nucleus of cells and functions in the brain, specifically in the anterior visceral endoderm and, subsequently, in the anterior definitive endoderm, anterior neuroectoderm, anterior mesendoderm, headfolds and forebrain. CNBP is necessary for the forebrain induction and specification, and mutations in the CNBP gene lead to severe forebrain truncation as well as various craniofacial defects due to a lack of proper morphogenetic movements of the anterior visceral endoderm during the pre-gastrulation stage. Overexpression of CNBP activates cell proliferation and stimulates the activity of the c-Myc promoter.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of ZNF9 pAb at 1:500 dilutionLane1:MCF-7 cell lysateLane2:Raw264.7 cell lysateLane3:Mouse brain tissue lysate