TMEM87B

This gene encodes a protein that may interact with human papillomavirus type 18 E6 oncogene. The protein is also likely to be involved in endosome-to-trans-Golgi network retrograde transport. The gene is expressed in adult and fetal tissues, including brain and heart. This gene is a component of the 2q13 deletion syndrome. Mutations in this gene may be associated with congenital heart defects. [provided by RefSeq, Aug 2016]

Description

Transmembrane protein 87B

Tissue specificity

Low tissue specificity

Subcell location

Golgi apparatus, Vesicles

Predicted location

Membrane

Protein family

Disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

2 (112055269 - 112119318)

Ensembl ID

ENSG00000153214  (ver. 103.38)

Orthologs

Mouse Tmem87b: ENSMUSG00000014353

UniProt

Q96K49

neXtProt

NX_Q96K49

Human splice variants
Mouse splice variants

Protein structure