RPS5

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Description

Ribosomal protein S5

Tissue specificity

Low tissue specificity

Subcell location

Endoplasmic reticulum, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Ribosomal proteins

Chromosome

19 (58386400 - 58394806)

Ensembl ID

ENSG00000083845  (ver. 103.38)

Orthologs

Mouse Rps5: ENSMUSG00000012848

UniProt

P46782

neXtProt

NX_P46782

Human splice variants
Mouse splice variants

Protein structure