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Cell line expression
Protein structure
GADD45A
Growth arrest and DNA damage inducible alphaDDIT1, GADD45
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Top validated antibodies |
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| Novus Biologicals |  H00001647-M01 |
4 references | Monoclonal |
WB
EL
IHC
PLA
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| Proteintech Group | 13747-1-AP |
12 references | Polyclonal |
WB
EL
IP
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| antibodies-online | ABIN2839408 |
5 references | Polyclonal |
WB
FC
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| Bioss | bs-1360R |
1 references | Polyclonal |
WB
ICC
IHC
FC
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| Affinity Biosciences | DF6622 |
Polyclonal |
WB
EL
ICC
IHC
|
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