POLR2D

This gene encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimal growth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the 3' untranslated region of the transcript from this gene. [provided by RefSeq, Jul 2008]

Description

RNA polymerase II subunit D

Tissue specificity

Tissue enhanced (testis)

Subcell location

Nucleoplasm, Nuclear speckles

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
RNA polymerase related proteins

Chromosome

2 (127843553 - 127858155)

Ensembl ID

ENSG00000144231  (ver. 103.38)

Orthologs

Mouse Polr2d: ENSMUSG00000024258

UniProt

O15514

neXtProt

NX_O15514

Human splice variants
Mouse splice variants

Protein structure