Tissue expression
Cell line expression
Protein structure
HNMT
Histamine N-methyltransferaseIn mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 11874-1-AP | 1 references | Polyclonal |
WB
EL
ICC
IHC |
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antibodies-online | ABIN2847276 | 1 references | Polyclonal |
WB
ICC
IHC
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GeneTex | GTX54118 | Polyclonal |
WB
ICC
IP
IHC |
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Invitrogen Antibodies | PA5-109825 | Polyclonal |
WB
ICC
IP
OA |
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LSBio | LS-C332135 | Polyclonal |
WB
ICC
IP
IHC |
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