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LearnALX-804-243-C100
antibody from Enzo Life Sciences
Targeting: TNFSF11
CD254, ODF, OPGL, RANKL, TRANCE
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunocytochemistry [2]
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- Product number
- ALX-804-243-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-804-243-C100, RRID:AB_2052453
- Product name
- RANKL monoclonal antibody (12A668)
- Antibody type
- Monoclonal
- Antigen
- Recombinant protein fragment
- Description
- Protein G-affinity purified.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 12A668
- Vial size
- 100 μg
- Storage
- -20°C
Submitted references Gamma-glutamyltranspeptidase stimulates receptor activator of nuclear factor-kappaB ligand expression independent of its enzymatic activity and serves as a pathological bone-resorbing factor.
Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression.
Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines.
Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors.
Niida S, Kawahara M, Ishizuka Y, Ikeda Y, Kondo T, Hibi T, Suzuki Y, Ikeda K, Taniguchi N
The Journal of biological chemistry 2004 Feb 13;279(7):5752-6
The Journal of biological chemistry 2004 Feb 13;279(7):5752-6
Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression.
Pearse RN, Sordillo EM, Yaccoby S, Wong BR, Liau DF, Colman N, Michaeli J, Epstein J, Choi Y
Proceedings of the National Academy of Sciences of the United States of America 2001 Sep 25;98(20):11581-6
Proceedings of the National Academy of Sciences of the United States of America 2001 Sep 25;98(20):11581-6
Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines.
Fiumara P, Snell V, Li Y, Mukhopadhyay A, Younes M, Gillenwater AM, Cabanillas F, Aggarwal BB, Younes A
Blood 2001 Nov 1;98(9):2784-90
Blood 2001 Nov 1;98(9):2784-90
Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors.
Kikuchi T, Matsuguchi T, Tsuboi N, Mitani A, Tanaka S, Matsuoka M, Yamamoto G, Hishikawa T, Noguchi T, Yoshikai Y
Journal of immunology (Baltimore, Md. : 1950) 2001 Mar 1;166(5):3574-9
Journal of immunology (Baltimore, Md. : 1950) 2001 Mar 1;166(5):3574-9
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis of RANKL in transfected cells using MAb to RANKL (12A668) (Prod. No. ALX-804-243).
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunohistochemical staining of RANKL in formalin-fixed, paraffin embedded human lymph node using MAb to RANKL (Prod. No. ALX-804-243) at 5µg/ml. Hematoxylin-eosin counterstain.
