Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
DDX58
DExD/H-box helicase 58DKFZp434J1111, FLJ13599, RIG-1, RIG-I, RIG1
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2. [provided by RefSeq, Aug 2020]
Top validated antibodies |
|||||
| Invitrogen Antibodies |  MA5-31715 |
2 references | Monoclonal |
WB
EL
ICC
FC
OA
|
|
| Proteintech Group | 20566-1-AP |
18 references | Polyclonal |
WB
EL
ICC
IP
|
|
| Novus Biologicals | NBP1-76732 |
1 references | Polyclonal |
WB
EL
ICC
IHC
|
|
| antibodies-online | ABIN4880676 |
Monoclonal |
WB
EL
ICC
FC
|
||
| GeneTex | GTX85488 |
3 references | Polyclonal |
WB
EL
IHC
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider