DPYD

gene product
DPD
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
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1 antibody
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Signalway Antibody LLC
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MyBioSource
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EMD Millipore
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Leading Biology
1 antibody
Sigma-Aldrich
1 antibody
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ProSci
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