HSPE1

This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3. [provided by RefSeq, Feb 2011]

Description

Heat shock protein family E (Hsp10) member 1

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Cancer-related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

2 (197500140 - 197503449)

Ensembl ID

ENSG00000115541  (ver. 103.38)

Orthologs

-

UniProt

P61604

neXtProt

NX_P61604

Human splice variants

Protein structure