Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
HRG
Histidine rich glycoproteinHPRG, HRGP
This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. [provided by RefSeq, Nov 2014]
Top validated antibodies |
|||||
| Novus Biologicals |  H00003273-B01P |
4 references | Polyclonal |
WB
EL
|
|
| LSBio | LS-C100915 |
Polyclonal |
WB
IHC
|
||
| Proteintech Group | 26252-1-AP |
1 references | Polyclonal |
WB
EL
|
|
| antibodies-online | ABIN516692 |
4 references | Polyclonal |
WB
|
|
| Abnova Corporation | H00003273-B01P |
4 references | Polyclonal |
WB
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider