Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10414-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10414-1-AP, RRID:AB_2063400
- Product name
- BCAS2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated BCAS2 antibody (Cat. #10414-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, monkey and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis.
BCAS2 interacts with HSF4 and negatively regulates its protein stability via ubiquitination.
BCAS2 promotes prostate cancer cells proliferation by enhancing AR mRNA transcription and protein stability.
Liu W, Wang F, Xu Q, Shi J, Zhang X, Lu X, Zhao ZA, Gao Z, Ma H, Duan E, Gao F, Gao S, Yi Z, Li L
Nature communications 2017 Jan 27;8:14182
Nature communications 2017 Jan 27;8:14182
BCAS2 interacts with HSF4 and negatively regulates its protein stability via ubiquitination.
Liao S, Du R, Wang L, Qu Z, Cui X, Li C, Liu F, Huang M, Wang J, Chen J, Gao M, Yu S, Tang Z, Li DW, Jiang T, Liu M
The international journal of biochemistry & cell biology 2015 Nov;68:78-86
The international journal of biochemistry & cell biology 2015 Nov;68:78-86
BCAS2 promotes prostate cancer cells proliferation by enhancing AR mRNA transcription and protein stability.
Kuo PC, Huang CW, Lee CI, Chang HW, Hsieh SW, Chung YP, Lee MS, Huang CS, Tsao LP, Tsao YP, Chen SL
British journal of cancer 2015 Jan 20;112(2):391-402
British journal of cancer 2015 Jan 20;112(2):391-402
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 10414-1-AP(BCAS2 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using BCAS2 antibody 10414-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-BCAS2 (IP:10414-1-AP, 3ug; Detection:10414-1-AP 1:1000) with mouse brain tissue lysate 6500ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 10414-1-AP(BCAS2 antibody) at dilution of 1:100 (under 25x lens)
- Sample type
- tissue