H2AC20

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. [provided by RefSeq, Aug 2015]

Description

H2A clustered histone 20

Tissue specificity

Group enriched (bone marrow, brain, choroid plexus)

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

1 (149886918 - 149887411)

Ensembl ID

ENSG00000184260  (ver. 103.38)

Orthologs

Mouse H2ac20: ENSMUSG00000068855

UniProt

Q16777

neXtProt

NX_Q16777

Human splice variants
Mouse splice variants

Protein structure