Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 19530-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19530-1-AP, RRID:AB_10642003
- Product name
- GATA4-Specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GATA4-Specific antibody (Cat. #19530-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Activation of GATA-binding protein 4 regulates monocyte chemoattractant protein-1 and chemotaxis in periodontal ligament cells.
Cartilage Endplate Stem Cells Transdifferentiate Into Nucleus Pulposus Cells via Autocrine Exosomes.
Generation and characterization of cardiac valve endothelial-like cells from human pluripotent stem cells.
Overexpressed WDR3 induces the activation of Hippo pathway by interacting with GATA4 in pancreatic cancer.
Proteome landscape and spatial map of mouse primordial germ cells.
Triptolide impairs glycolysis by suppressing GATA4/Sp1/PFKP signaling axis in mouse Sertoli cells.
ADNP Controls Gene Expression Through Local Chromatin Architecture by Association With BRG1 and CHD4.
Crosstalk between cardiomyocytes and noncardiomyocytes is essential to prevent cardiomyocyte apoptosis induced by proteasome inhibition.
Genome-wide translational reprogramming of genes important for myocyte functions in overload-induced heart failure.
Circular RNA circRNA_000203 aggravates cardiac hypertrophy via suppressing miR-26b-5p and miR-140-3p binding to Gata4.
Placental P-glycoprotein inhibition enhances susceptibility to Di-(2-ethylhexyl)-phthalate induced cardiac malformations in mice: A possibly promising target for congenital heart defects prevention.
GATA3 recruits UTX for gene transcriptional activation to suppress metastasis of breast cancer.
Induction of Sertoli-like cells from human fibroblasts by NR5A1 and GATA4.
miR-323-3p regulates the steroidogenesis and cell apoptosis in polycystic ovary syndrome (PCOS) by targeting IGF-1.
Silver Nanoparticles Compromise Female Embryonic Stem Cell Differentiation through Disturbing X Chromosome Inactivation.
The effect of maternal exposure to di-(2-ethylhexyl)-phthalate on fetal cardiac development in mice.
GATA4 is upregulated in nasopharyngeal cancer and facilitates epithelial-mesenchymal transition and metastasis through regulation of SLUG.
miR-200c regulates endothelin-1 induced PASMCs abnormal proliferation and apoptosis.
Apelin-13 infusion salvages the peri-infarct region to preserve cardiac function after severe myocardial injury.
Restoration of miR-98 relieves the inhibitory effect of nicotine on the differentiation of P19 cells into cardiomyocytes.
Identification of functional mutations in GATA4 in patients with congenital heart disease.
Zhu N, Zheng X, Qiao W, Huang W, Li R, Song Y
Journal of periodontal research 2022 Jan;57(1):195-204
Journal of periodontal research 2022 Jan;57(1):195-204
Cartilage Endplate Stem Cells Transdifferentiate Into Nucleus Pulposus Cells via Autocrine Exosomes.
Luo L, Gong J, Zhang H, Qin J, Li C, Zhang J, Tang Y, Zhang Y, Chen J, Zhou Y, Tian Z, Liu Y, Liu M
Frontiers in cell and developmental biology 2021;9:648201
Frontiers in cell and developmental biology 2021;9:648201
Generation and characterization of cardiac valve endothelial-like cells from human pluripotent stem cells.
Cheng L, Xie M, Qiao W, Song Y, Zhang Y, Geng Y, Xu W, Wang L, Wang Z, Huang K, Dong N, Sun Y
Communications biology 2021 Sep 6;4(1):1039
Communications biology 2021 Sep 6;4(1):1039
Overexpressed WDR3 induces the activation of Hippo pathway by interacting with GATA4 in pancreatic cancer.
Su W, Zhu S, Chen K, Yang H, Tian M, Fu Q, Shi G, Feng S, Ren D, Jin X, Yang C
Journal of experimental & clinical cancer research : CR 2021 Mar 1;40(1):88
Journal of experimental & clinical cancer research : CR 2021 Mar 1;40(1):88
Proteome landscape and spatial map of mouse primordial germ cells.
Wang P, Miao Y, Li XH, Zhang N, Wang Q, Yue W, Sun SC, Xiong B, Qiao J, Li M
Science China. Life sciences 2021 Jun;64(6):966-981
Science China. Life sciences 2021 Jun;64(6):966-981
Triptolide impairs glycolysis by suppressing GATA4/Sp1/PFKP signaling axis in mouse Sertoli cells.
Zhang Y, Tang Y, Luo Y, Luo L, Shen F, Huang Z
Toxicology and applied pharmacology 2021 Aug 15;425:115606
Toxicology and applied pharmacology 2021 Aug 15;425:115606
ADNP Controls Gene Expression Through Local Chromatin Architecture by Association With BRG1 and CHD4.
Sun X, Yu W, Li L, Sun Y
Frontiers in cell and developmental biology 2020;8:553
Frontiers in cell and developmental biology 2020;8:553
Crosstalk between cardiomyocytes and noncardiomyocytes is essential to prevent cardiomyocyte apoptosis induced by proteasome inhibition.
Guo F, Zhang CC, Yin XH, Li T, Fang CH, He XB
Cell death & disease 2020 Sep 19;11(9):783
Cell death & disease 2020 Sep 19;11(9):783
Genome-wide translational reprogramming of genes important for myocyte functions in overload-induced heart failure.
Guo Q, Zhang Y, Zhang S, Jin J, Pang S, Wu X, Zhang W, Bi X, Zhang Y, Zhang Q, Jiang F
Biochimica et biophysica acta. Molecular basis of disease 2020 Mar 1;1866(3):165649
Biochimica et biophysica acta. Molecular basis of disease 2020 Mar 1;1866(3):165649
Circular RNA circRNA_000203 aggravates cardiac hypertrophy via suppressing miR-26b-5p and miR-140-3p binding to Gata4.
Li H, Xu JD, Fang XH, Zhu JN, Yang J, Pan R, Yuan SJ, Zeng N, Yang ZZ, Yang H, Wang XP, Duan JZ, Wang S, Luo JF, Wu SL, Shan ZX
Cardiovascular research 2020 Jun 1;116(7):1323-1334
Cardiovascular research 2020 Jun 1;116(7):1323-1334
Placental P-glycoprotein inhibition enhances susceptibility to Di-(2-ethylhexyl)-phthalate induced cardiac malformations in mice: A possibly promising target for congenital heart defects prevention.
Tang C, Luo C, Hua Y, Zhou K, Duan H, Ma F, Zhang Y, Li Y, Qiu D, Wang C
PloS one 2019;14(5):e0214873
PloS one 2019;14(5):e0214873
GATA3 recruits UTX for gene transcriptional activation to suppress metastasis of breast cancer.
Yu W, Huang W, Yang Y, Qiu R, Zeng Y, Hou Y, Sun G, Shi H, Leng S, Feng D, Chen Y, Wang S, Teng X, Yu H, Wang Y
Cell death & disease 2019 Nov 4;10(11):832
Cell death & disease 2019 Nov 4;10(11):832
Induction of Sertoli-like cells from human fibroblasts by NR5A1 and GATA4.
Liang J, Wang N, He J, Du J, Guo Y, Li L, Wu W, Yao C, Li Z, Kee K
eLife 2019 Nov 11;8
eLife 2019 Nov 11;8
miR-323-3p regulates the steroidogenesis and cell apoptosis in polycystic ovary syndrome (PCOS) by targeting IGF-1.
Wang T, Liu Y, Lv M, Xing Q, Zhang Z, He X, Xu Y, Wei Z, Cao Y
Gene 2019 Jan 30;683:87-100
Gene 2019 Jan 30;683:87-100
Silver Nanoparticles Compromise Female Embryonic Stem Cell Differentiation through Disturbing X Chromosome Inactivation.
Zhang J, Chen Y, Gao M, Wang Z, Liu R, Xia T, Liu S
ACS nano 2019 Feb 26;13(2):2050-2061
ACS nano 2019 Feb 26;13(2):2050-2061
The effect of maternal exposure to di-(2-ethylhexyl)-phthalate on fetal cardiac development in mice.
Tang C, Deng Y, Duan H, Zhang Y, Li Y, Qiu D, Zhou K, Hua Y, Wang C
Journal of applied toxicology : JAT 2018 Jun;38(6):834-842
Journal of applied toxicology : JAT 2018 Jun;38(6):834-842
GATA4 is upregulated in nasopharyngeal cancer and facilitates epithelial-mesenchymal transition and metastasis through regulation of SLUG.
Zhou Y, Chang H, Yang B
Experimental and therapeutic medicine 2018 Dec;16(6):5318-5326
Experimental and therapeutic medicine 2018 Dec;16(6):5318-5326
miR-200c regulates endothelin-1 induced PASMCs abnormal proliferation and apoptosis.
Yuan C, Xu M, Rong R, Mei Y, Cai W, Li L, Xue Y, Zhu B, Sun K, Han L
IUBMB life 2017 Nov;69(11):877-886
IUBMB life 2017 Nov;69(11):877-886
Apelin-13 infusion salvages the peri-infarct region to preserve cardiac function after severe myocardial injury.
Chung WJ, Cho A, Byun K, Moon J, Ge X, Seo HS, Moon E, Dash R, Yang PC
International journal of cardiology 2016 Nov 1;222:361-367
International journal of cardiology 2016 Nov 1;222:361-367
Restoration of miR-98 relieves the inhibitory effect of nicotine on the differentiation of P19 cells into cardiomyocytes.
Ai F, Zhang Y, Peng B
Biotechnology letters 2016 Apr;38(4):579-87
Biotechnology letters 2016 Apr;38(4):579-87
Identification of functional mutations in GATA4 in patients with congenital heart disease.
Wang E, Sun S, Qiao B, Duan W, Huang G, An Y, Xu S, Zheng Y, Su Z, Gu X, Jin L, Wang H
PloS one 2013;8(4):e62138
PloS one 2013;8(4):e62138
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 19530-1-AP(GATA4-Specific antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GATA4-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human GATA4-Specific. This antibody recognizes human,mouse,rat antigen. The GATA4-Specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 19530-1-AP(GATA4-Specific antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue