Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- ELISA [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN393488 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-HCLS1 Associated Protein X-1 (HAX1) (AA 76-175) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 76-175
- Isotype
- IgG
- Antibody clone number
- 1D2
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Molecular interaction between HAX-1 and XIAP inhibits apoptosis.
Deregulation of mitochondrial membrane potential by mitochondrial insertion of granzyme B and direct Hax-1 cleavage.
Pelota interacts with HAX1, EIF3G and SRPX and the resulting protein complexes are associated with the actin cytoskeleton.
[Neurological findings in severe congenital neutropenia with HAX1 mutations].
A novel missense mutation in the HAX1 gene in severe congenital neutropenia patients (Kostmann disease).
Kang YJ, Jang M, Park YK, Kang S, Bae KH, Cho S, Lee CK, Park BC, Chi SW, Park SG
Biochemical and biophysical research communications 2010 Mar 19;393(4):794-9
Biochemical and biophysical research communications 2010 Mar 19;393(4):794-9
Deregulation of mitochondrial membrane potential by mitochondrial insertion of granzyme B and direct Hax-1 cleavage.
Han J, Goldstein LA, Hou W, Froelich CJ, Watkins SC, Rabinowich H
The Journal of biological chemistry 2010 Jul 16;285(29):22461-72
The Journal of biological chemistry 2010 Jul 16;285(29):22461-72
Pelota interacts with HAX1, EIF3G and SRPX and the resulting protein complexes are associated with the actin cytoskeleton.
Burnicka-Turek O, Kata A, Buyandelger B, Ebermann L, Kramann N, Burfeind P, Hoyer-Fender S, Engel W, Adham IM
BMC cell biology 2010 Apr 20;11:28
BMC cell biology 2010 Apr 20;11:28
[Neurological findings in severe congenital neutropenia with HAX1 mutations].
Ishikawa N, Kobayashi M
No to hattatsu = Brain and development 2009 Nov;41(6):415-9
No to hattatsu = Brain and development 2009 Nov;41(6):415-9
A novel missense mutation in the HAX1 gene in severe congenital neutropenia patients (Kostmann disease).
Faiyaz-Ul-Haque M, Al-Jefri A, Abalkhail HA, Toulimat M, Al-Muallimi MA, Pulicat MS, Gaafar A, Alaiya AA, Al-Dayel F, Peltekova I, Zaidi SH
Clinical genetics 2009 Dec;76(6):569-72
Clinical genetics 2009 Dec;76(6):569-72
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA
