10841-1-AP

antibody from Proteintech Group

Targeting: STX6

Provider product page for 10841-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [13]
Comments [0]
Validations
Western blot [1]
Immunoprecipitation [1]

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Product number: 10841-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#10841-1-AP, RRID:AB_2196506
Product name: Syntaxin 6 antibody
Antibody type: Polyclonal
Description: KD/KO validated Syntaxin 6 antibody (Cat. #10841-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

STX6 protein structure - 10841-1-AP shown in red.

Submitted references Thioxothiazolidin derivative, 4-OST, inhibits melanogenesis by enhancing the specific recruitment of tyrosinase-containing vesicles to lysosome.

Isogawa K, Asano M, Hayazaki M, Koga K, Watanabe M, Suzuki K, Kobayashi T, Kawaguchi K, Ishizuka A, Kato S, Ito H, Hamamoto A, Koyama H, Furuta K, Takemori H
Journal of cellular biochemistry 2021 Jun;122(6):667-678

Compromised mitochondrial quality control triggers lipin1-related rhabdomyolysis.

Hamel Y, Mauvais FX, Madrange M, Renard P, Lebreton C, Nemazanyy I, Pellé O, Goudin N, Tang X, Rodero MP, Tuchmann-Durand C, Nusbaum P, Brindley DN, van Endert P, de Lonlay P
Cell reports. Medicine 2021 Aug 17;2(8):100370

IRAP Endosomes Control Phagosomal Maturation in Dendritic Cells.

Weimershaus M, Mauvais FX, Evnouchidou I, Lawand M, Saveanu L, van Endert P
Frontiers in cell and developmental biology 2020;8:585713

IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses.

Evnouchidou I, Chappert P, Benadda S, Zucchetti A, Weimershaus M, Bens M, Caillens V, Koumantou D, Lotersztajn S, van Endert P, Davoust J, Guermonprez P, Hivroz C, Gross DA, Saveanu L
Nature communications 2020 Jun 2;11(1):2779

Phosphoproteomics reveals that the hVPS34 regulated SGK3 kinase specifically phosphorylates endosomal proteins including Syntaxin-7, Syntaxin-12, RFIP4 and WDR44.

Malik N, Nirujogi RS, Peltier J, Macartney T, Wightman M, Prescott AR, Gourlay R, Trost M, Alessi DR, Karapetsas A
The Biochemical journal 2019 Oct 30;476(20):3081-3107

Proteomic analysis of insulin secretory granules in INS-1 cells by protein correlation profiling.

Li M, Du W, Zhou M, Zheng L, Song E, Hou J
Biophysics reports 2018;4(6):329-338

Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation.

Weimershaus M, Mauvais FX, Saveanu L, Adiko C, Babdor J, Abramova A, Montealegre S, Lawand M, Evnouchidou I, Huber KJ, Chadt A, Zwick M, Vargas P, Dussiot M, Lennon-Dumenil AM, Brocker T, Al-Hasani H, van Endert P
Cell reports 2018 Sep 25;24(13):3568-3581

MARCH9-mediated ubiquitination regulates MHC I export from the TGN.

De Angelis Rigotti F, De Gassart A, Pforr C, Cano F, N'Guessan P, Combes A, Camossetto V, Lehner PJ, Pierre P, Gatti E
Immunology and cell biology 2017 Oct;95(9):753-764

IRAP⁺ endosomes restrict TLR9 activation and signaling.

Babdor J, Descamps D, Adiko AC, Tohmé M, Maschalidi S, Evnouchidou I, Vasconcellos LR, De Luca M, Mauvais FX, Garfa-Traore M, Brinkmann MM, Chignard M, Manoury B, Saveanu L
Nature immunology 2017 May;18(5):509-518

Over-expression of microRNA-1 causes arrhythmia by disturbing intracellular trafficking system.

Su X, Liang H, Wang H, Chen G, Jiang H, Wu Q, Liu T, Liu Q, Yu T, Gu Y, Yang B, Shan H
Scientific reports 2017 Apr 11;7:46259

Conventional dendritic cells require IRAP-Rab14 endosomes for efficient cross-presentation.

Weimershaus M, Maschalidi S, Sepulveda F, Manoury B, van Endert P, Saveanu L
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 15;188(4):1840-6

HID-1 is a peripheral membrane protein primarily associated with the medial- and trans- Golgi apparatus.

Wang L, Zhan Y, Song E, Yu Y, Jiu Y, Du W, Lu J, Liu P, Xu P, Xu T
Protein & cell 2011 Jan;2(1):74-85

IRAP identifies an endosomal compartment required for MHC class I cross-presentation.

Saveanu L, Carroll O, Weimershaus M, Guermonprez P, Firat E, Lindo V, Greer F, Davoust J, Kratzer R, Keller SR, Niedermann G, van Endert P
Science (New York, N.Y.) 2009 Jul 10;325(5937):213-7

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: mouse brain tissue were subjected to SDS PAGE followed by western blot with 10841-1-AP(STX6 antibody) at dilution of 1:2000
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: IP Result of anti-STX6 (IP:10841-1-AP, 3ug; Detection:10841-1-AP 1:1000) with mouse brain tissue lysate 7000ug.
Sample type: tissue