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Protein structure
CRB1
Crumbs cell polarity complex component 1LCA8, RP12
This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding. [provided by RefSeq, Apr 2012]
Top validated antibodies |
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| Boster Biological Technology |  A01499 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| NSJ Bioreagents | RQ4372 |
Polyclonal |
WB
EL
IHC
FC
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| NovoPro Bioscience Inc. | 127106 |
Polyclonal |
WB
EL
IHC
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| Cusabio Biotech Co., Ltd | CSB-PA005941DSR1HU |
Polyclonal |
EL
ICC
IHC
|
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| LSBio | LS-C662538 |
Polyclonal |
WB
EL
IHC
|
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