Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Flow cytometry [1]
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Validation data
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- Product number
- ABIN951451 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila) (DTL) (AA 229-256), (Middle Region) antibody
- Antibody type
- Polyclonal
- Description
- Affinity Chromatography on Protein A
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 229-256, Middle Region
- Vial size
- 0.4 mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation.
CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase.
PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex.
Abbas T, Shibata E, Park J, Jha S, Karnani N, Dutta A
Molecular cell 2010 Oct 8;40(1):9-21
Molecular cell 2010 Oct 8;40(1):9-21
CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase.
Centore RC, Havens CG, Manning AL, Li JM, Flynn RL, Tse A, Jin J, Dyson NJ, Walter JC, Zou L
Molecular cell 2010 Oct 8;40(1):22-33
Molecular cell 2010 Oct 8;40(1):22-33
PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex.
Abbas T, Sivaprasad U, Terai K, Amador V, Pagano M, Dutta A
Genes & development 2008 Sep 15;22(18):2496-506
Genes & development 2008 Sep 15;22(18):2496-506
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS