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BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| antibodies-online |  ABIN394459 |
5 references | Monoclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | H00010380-M01 |
Monoclonal |
WB
EL
ICC
IHC
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| Abnova Corporation | H00010380-M01 |
Monoclonal |
WB
EL
ICC
IHC
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| Proteintech Group | 16461-1-AP |
Polyclonal |
WB
EL
ICC
IHC
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| LSBio | LS-C133641 |
Monoclonal |
WB
EL
ICC
IHC
|
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