APR04167G
antibody from Leading Biology
Targeting: LILRB1
CD85, CD85j, ILT2, LIR-1, LIR1, MIR-7, PIR-B, PIRB
Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APR04167G - Provider product page
- Provider
- Leading Biology
- Product name
- LILRB1 Antibody (Center)
- Antibody type
- Polyclonal
- Description
- This gene is a member of the leukocyte immunoglobulin-likereceptor (LIR) family, which is found in a gene cluster atchromosomal region 19q13.4. The encoded protein belongs to thesubfamily B class of LIR receptors which contain two or fourextracellular immunoglobulin domains, a transmembrane domain, andtwo to four cytoplasmic immunoreceptor tyrosine-based inhibitorymotifs (ITIMs). The receptor is expressed on immune cells where itbinds to MHC class I molecules on antigen-presenting cells andtransduces a negative signal that inhibits stimulation of an immuneresponse. It is thought to control inflammatory responses andcytotoxicity to help focus the immune response and limitautoreactivity. Multiple transcript variants encoding differentisoforms have been found for this gene.
- Reactivity
- Human
- Host
- Rabbit
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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