TTC4

This gene encodes a protein that contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions and chaperone activity. The encoded protein interacts with heat shock proteins 70 and 90. Alternative splicing results in multiple transcript variants. Naturally-occuring readthrough transcription occurs from upstream gene MROH (maestro heat-like repeat family member 7) to this gene. [provided by RefSeq, Apr 2014]

Description

Tetratricopeptide repeat domain 4

Tissue specificity

Low tissue specificity

Subcell location

Intermediate filaments, Cytoplasmic bodies

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

1 (54715861 - 54742657)

Ensembl ID

ENSG00000243725  (ver. 103.38)

Orthologs

Mouse Ttc4: ENSMUSG00000025413

UniProt

O95801

neXtProt

NX_O95801

Human splice variants
Mouse splice variants

Protein structure