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CD3E
CD3e moleculeThe protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  17617-1-AP |
34 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| GeneTex | GTX42110 |
2 references | Monoclonal |
WB
EL
ICC
IHC
FC
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| NSJ Bioreagents | V3462 |
23 references | Monoclonal |
WB
ICC
IHC
FC
OA
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| R&D Systems | MAB4841-100 |
18 references | Monoclonal |
ICC
IP
IHC
FC
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| Novus Biologicals | NBP1-26685 |
6 references | Monoclonal |
IP
IHC
FC
FA
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