Antibody data

Product number
36-3010 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-CD34 Antibody
Antibody type
Monoclonal
Description
CD34 a type 1 transmembrane protein, belonging to the sialomucin family, has important roles in adhesion which remain to be fully elucidated. CD34 has an intracellular cytoplasmic domain containing consensus sites for serine, theronine, tryrosine and active protein kinase C (PKC) phosphorylation thereby implicating a role for the protein in signal transduction processes. CD34 expression, as identified by antibody, is a hallmark for identifying pluripotential hematopoietic stem or progenitor cells. CD34 antibody positive populations expand and differentiate into the various lymphohematopoietic lineages. During differentiation, lineages lose CD34 expression and become CD34 antibody negative.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
Blast cells from a chronic myeloid
leukemia patient were used as the i
mmunogen for the CD34 antibody.
Isotype
IgG
Antibody clone number
ICO-115
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
CD34 protein structure - 36-3010 shown in red.