Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- 36-3010 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-CD34 Antibody
- Antibody type
- Monoclonal
- Description
- CD34 a type 1 transmembrane protein, belonging to the sialomucin family, has important roles in adhesion which remain to be fully elucidated. CD34 has an intracellular cytoplasmic domain containing consensus sites for serine, theronine, tryrosine and active protein kinase C (PKC) phosphorylation thereby implicating a role for the protein in signal transduction processes. CD34 expression, as identified by antibody, is a hallmark for identifying pluripotential hematopoietic stem or progenitor cells. CD34 antibody positive populations expand and differentiate into the various lymphohematopoietic lineages. During differentiation, lineages lose CD34 expression and become CD34 antibody negative.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
Blast cells from a chronic myeloid
leukemia patient were used as the i
mmunogen for the CD34 antibody.- Isotype
- IgG
- Antibody clone number
- ICO-115
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Cell Surface flow analysis of hCD34 on KG-1 cells using 0.5 µg antibody per 10^6 cells. Green represents isotype control (ABEOMICS); red represents anti-hCD34 antibody (36-3010). Goat anti-mouse PE conjugated secondary antibody was used (ABEOMICS).