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- Antigen structure
- References [8]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12162-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12162-1-AP, RRID:AB_2177360
- Product name
- RAB39B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RAB39B antibody (Cat. #12162-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies.
RAB39B Deficiency Impairs Learning and Memory Partially Through Compromising Autophagy.
Distribution of Parkinson's disease associated RAB39B in mouse brain tissue.
Clinical and Neuropathological Features Associated With Loss of RAB39B.
Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels.
Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.
Mutations in RAB39B cause X-linked intellectual disability and early-onset Parkinson disease with α-synuclein pathology.
Identification and characterization of multiple novel Rab-myosin Va interactions.
Koss DJ, Bondarevaite O, Adams S, Leite M, Giorgini F, Attems J, Outeiro TF
Brain pathology (Zurich, Switzerland) 2021 Jan;31(1):120-132
Brain pathology (Zurich, Switzerland) 2021 Jan;31(1):120-132
RAB39B Deficiency Impairs Learning and Memory Partially Through Compromising Autophagy.
Niu M, Zheng N, Wang Z, Gao Y, Luo X, Chen Z, Fu X, Wang Y, Wang T, Liu M, Yao T, Yao P, Meng J, Zhou Y, Ge Y, Wang Z, Ma Q, Xu H, Zhang YW
Frontiers in cell and developmental biology 2020;8:598622
Frontiers in cell and developmental biology 2020;8:598622
Distribution of Parkinson's disease associated RAB39B in mouse brain tissue.
Gao Y, Wilson GR, Stephenson SEM, Oulad-Abdelghani M, Charlet-Berguerand N, Bozaoglu K, McLean CA, Thomas PQ, Finkelstein DI, Lockhart PJ
Molecular brain 2020 Mar 30;13(1):52
Molecular brain 2020 Mar 30;13(1):52
Clinical and Neuropathological Features Associated With Loss of RAB39B.
Gao Y, Martínez-Cerdeño V, Hogan KJ, McLean CA, Lockhart PJ
Movement disorders : official journal of the Movement Disorder Society 2020 Apr;35(4):687-693
Movement disorders : official journal of the Movement Disorder Society 2020 Apr;35(4):687-693
Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels.
Xiao S, McKeever PM, Lau A, Robertson J
Acta neuropathologica communications 2019 Oct 24;7(1):161
Acta neuropathologica communications 2019 Oct 24;7(1):161
Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.
Sellier C, Campanari ML, Julie Corbier C, Gaucherot A, Kolb-Cheynel I, Oulad-Abdelghani M, Ruffenach F, Page A, Ciura S, Kabashi E, Charlet-Berguerand N
The EMBO journal 2016 Jun 15;35(12):1276-97
The EMBO journal 2016 Jun 15;35(12):1276-97
Mutations in RAB39B cause X-linked intellectual disability and early-onset Parkinson disease with α-synuclein pathology.
Wilson GR, Sim JC, McLean C, Giannandrea M, Galea CA, Riseley JR, Stephenson SE, Fitzpatrick E, Haas SA, Pope K, Hogan KJ, Gregg RG, Bromhead CJ, Wargowski DS, Lawrence CH, James PA, Churchyard A, Gao Y, Phelan DG, Gillies G, Salce N, Stanford L, Marsh AP, Mignogna ML, Hayflick SJ, Leventer RJ, Delatycki MB, Mellick GD, Kalscheuer VM, D'Adamo P, Bahlo M, Amor DJ, Lockhart PJ
American journal of human genetics 2014 Dec 4;95(6):729-35
American journal of human genetics 2014 Dec 4;95(6):729-35
Identification and characterization of multiple novel Rab-myosin Va interactions.
Lindsay AJ, Jollivet F, Horgan CP, Khan AR, Raposo G, McCaffrey MW, Goud B
Molecular biology of the cell 2013 Nov;24(21):3420-34
Molecular biology of the cell 2013 Nov;24(21):3420-34
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 12162-1-AP(RAB39B antibody) at dilution of 1:200
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RAB39B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RAB39B. This antibody recognizes human, mouse, rat antigen. The RAB39B antibody has been validated for the following applications: ELISA, WB, IHC analysis.
