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- Antibody Data
- Antigen structure
- References [5]
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- Product number
- AF1041 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal TACI/TNFRSF13B/CVID Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse TACI/TNFRSF13B in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human TACI is observed and less than 1% cross-reactivity with recombinant mouse BCMA/TNFRSF17 is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells.
The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88.
Functional implication of BAFF synthesis and release in gangliosides-stimulated microglia.
Deficient TACI expression on B lymphocytes of newborn mice leads to defective Ig secretion in response to BAFF or APRIL.
Deficient TACI expression on B lymphocytes of newborn mice leads to defective Ig secretion in response to BAFF or APRIL.
Saulep-Easton D, Vincent FB, Quah PS, Wei A, Ting SB, Croce CM, Tam C, Mackay F
Leukemia 2016 Jan;30(1):163-72
Leukemia 2016 Jan;30(1):163-72
The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88.
He B, Santamaria R, Xu W, Cols M, Chen K, Puga I, Shan M, Xiong H, Bussel JB, Chiu A, Puel A, Reichenbach J, Marodi L, Döffinger R, Vasconcelos J, Issekutz A, Krause J, Davies G, Li X, Grimbacher B, Plebani A, Meffre E, Picard C, Cunningham-Rundles C, Casanova JL, Cerutti A
Nature immunology 2010 Sep;11(9):836-45
Nature immunology 2010 Sep;11(9):836-45
Functional implication of BAFF synthesis and release in gangliosides-stimulated microglia.
Kim KS, Park JY, Jou I, Park SM
Journal of leukocyte biology 2009 Aug;86(2):349-59
Journal of leukocyte biology 2009 Aug;86(2):349-59
Deficient TACI expression on B lymphocytes of newborn mice leads to defective Ig secretion in response to BAFF or APRIL.
Kanswal S, Katsenelson N, Selvapandiyan A, Bram RJ, Akkoyunlu M
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 15;181(2):976-90
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 15;181(2):976-90
Deficient TACI expression on B lymphocytes of newborn mice leads to defective Ig secretion in response to BAFF or APRIL.
Kanswal S, Katsenelson N, Selvapandiyan A, Bram RJ, Akkoyunlu M
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 15;181(2):976-90
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 15;181(2):976-90
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