14-9217-80

TNFRSF13B antibody from Invitrogen Antibodies
CD267, IGAD2, TACI
Flow cytometry
Supportive data in Antibodypedia
Other assay
Recommended by provider

Antibody data

Product number
14-9217-80
Provider
Invitrogen Antibodies
Product name
Anti-CD267 (TACI) Monoclonal Antibody (11H3), eBioscience™
Provider product page
Invitrogen Antibodies - 14-9217-80
Antibody type
Monoclonal
Antigen
Other
Description
Description: The 11H3 antibody reacts with human TACI, also known as tumor necrosis factor receptor 13B. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. TACI mRNA and protein are found predominantly in B-cells and correlate with BLyS binding in a panel of B-cell lines. TACI interacts with nanomolar affinity with the BLyS-related tumor necrosis factor homologue APRIL for which no clear in vivo role has been described. 11H3 does not block binding of BAFF/BLyS to TACI. Applications Reported: This 11H3 antibody has been reported for use in flow cytometric analysis. (Please use Functional Grade purified 11H3, cat. 16-9217, in functional assays.). Applications Tested: This 11H3 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
11H3
Vial size
25 µg
Concentration
0.5 mg/mL
Storage
4° C
Provider Type Product Number
- No reagents -