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- Antibody Data
- Antigen structure
- References [32]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN343541 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN343541, RRID:AB_10796267
- Product name
- anti-Tumor Protein P53 (TP53) antibody
- Antibody type
- Monoclonal
- Antigen
- Recombinant human wild-type p53 protein. Purification Purified by the goat anti-mouse IgG affinity chromatography.
- Reactivity
- Human
- Isotype
- IgG
- Antibody clone number
- IMD-53
- Vial size
- 100 µg
- Storage
- At -20°C for one year. After reconstitution, at 4°C for three month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100µg/ml.
Submitted references Dracorhodin perchlorate inhibits PI3K/Akt and NF-κB activation, up-regulates the expression of p53, and enhances apoptosis.
Stat6 activity-related Th2 cytokine profile and tumor growth advantage of human colorectal cancer cells in vitro and in vivo.
Coexpression of the mutated BRCA1 mRNA and p53 mRNA and its association in Chinese prostate cancer.
Apoptotic mechanism of MCF-7 breast cells in vivo and in vitro induced by photodynamic therapy with C-phycocyanin.
Mesenchymal stem cell-like cells derived from human gastric cancer tissues.
Inhibitory effect of extract of fungi of Huaier on hepatocellular carcinoma cells.
Inhibitory effects of Baicalin on ultraviolet B-induced photo-damage in keratinocyte cell line.
Effect of Jinguo Weikang Capsule on proto-oncogene expression of gastric mucosa in rats with gastric precancerous lesions.
P53 transcription-independent activity mediates selenite-induced acute promyelocytic leukemia NB4 cell apoptosis.
Telomerase catalyzed fluorescent probes for sensitive protein profiling based on one-dimensional microfluidic beads array.
Knockdown of survivin and upregulation of p53 gene expression by small interfering RNA induces apoptosis in human gastric carcinoma cell line SGC-823.
IFITM1 plays an essential role in the antiproliferative action of interferon-gamma.
Expression of hTERT, p53 and PCNA in cystitis glandularis.
Trans-arterial gene therapy for hepatocellular carcinoma in a rabbit model.
Expression of Egr-1 gene and its correlation with the oncogene proteins in non-irradiated and irradiated esophageal squamous cell carcinoma.
Quantitative intracellular molecular profiling using a one-dimensional flow system.
Effects of tachyplesin and n-sodium butyrate on proliferation and gene expression of human gastric adenocarcinoma cell line BGC-823.
Expression of BIRC7 protein and mRNA in non-Hodgkin's lymphoma.
Radiosensitivity of human colon cancer cell enhanced by immunoliposomal docetaxel.
Effects of sulfur dioxide on apoptosis-related gene expressions in lungs from rats.
Expression of apoptosis-related genes in livers from rats exposed to sulfur dioxide.
Growth-inhibitory effects of curcumin on ovary cancer cells and its mechanisms.
Effects of novel safrole oxide derivatives, 1-propyl-3-(3,4-methylenedioxyphenyl)-2-propanol and 1-isopropoxy-3-(3,4-methylenedioxyphenyl)-2-propanol, on apoptosis induced by deprivation of survival factors in vascular endothelial cells.
Cytochrome C oxidase III interacts with hepatitis B virus X protein in vivo by yeast two-hybrid system.
Effects of Chinese medicinal fungus water extract on tumor metastasis and some parameters of immune function.
Integrin beta4 mAb inhibited apoptosis induced by deprivation of growth factors in vascular endothelial cells.
BAK overexpression mediates p53-independent apoptosis inducing effects on human gastric cancer cells.
Integrin beta 4 is a target of rattlesnake venom during inducing apoptosis of vascular endothelial cells.
Apoptosis mediated by phosphatidylcholine-specific phospholipase C is associated with cAMP, p53 level, and cell-cycle distribution in vascular endothelial cells.
Helicobacter pylori infection generated gastric cancer through p53-Rb tumor-suppressor system mutation and telomerase reactivation.
Study on apoptosis and expression of P53, bcl-2, Bax in cardiac myocytys of congestive heart failure induced by ventricular pacing.
P21WAF1/Cip1 gene expression in primary human hepatocellular carcinoma and its relationship with P53 gene mutation.
Rasul A, Ding C, Li X, Khan M, Yi F, Ali M, Ma T
Apoptosis : an international journal on programmed cell death 2012 Oct;17(10):1104-19
Apoptosis : an international journal on programmed cell death 2012 Oct;17(10):1104-19
Stat6 activity-related Th2 cytokine profile and tumor growth advantage of human colorectal cancer cells in vitro and in vivo.
Li BH, Xu SB, Li F, Zou XG, Saimaiti A, Simayi D, Wang YH, Zhang Y, Yuan J, Zhang WJ
Cellular signalling 2012 Mar;24(3):718-25
Cellular signalling 2012 Mar;24(3):718-25
Coexpression of the mutated BRCA1 mRNA and p53 mRNA and its association in Chinese prostate cancer.
Ding GF, Xu YF, Yang ZS, Ding YL, Fang HF, Zhao HP
Urologic oncology 2011 Mar-Apr;29(2):145-9
Urologic oncology 2011 Mar-Apr;29(2):145-9
Apoptotic mechanism of MCF-7 breast cells in vivo and in vitro induced by photodynamic therapy with C-phycocyanin.
Li B, Chu X, Gao M, Li W
Acta biochimica et biophysica Sinica 2010 Jan;42(1):80-9
Acta biochimica et biophysica Sinica 2010 Jan;42(1):80-9
Mesenchymal stem cell-like cells derived from human gastric cancer tissues.
Cao H, Xu W, Qian H, Zhu W, Yan Y, Zhou H, Zhang X, Xu X, Li J, Chen Z, Xu X
Cancer letters 2009 Feb 8;274(1):61-71
Cancer letters 2009 Feb 8;274(1):61-71
Inhibitory effect of extract of fungi of Huaier on hepatocellular carcinoma cells.
Ren J, Zheng C, Feng G, Liang H, Xia X, Fang J, Duan X, Zhao H
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2009 Apr;29(2):198-201
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2009 Apr;29(2):198-201
Inhibitory effects of Baicalin on ultraviolet B-induced photo-damage in keratinocyte cell line.
Min W, Lin XF, Miao X, Wang BT, Yang ZL, Luo D
The American journal of Chinese medicine 2008;36(4):745-60
The American journal of Chinese medicine 2008;36(4):745-60
Effect of Jinguo Weikang Capsule on proto-oncogene expression of gastric mucosa in rats with gastric precancerous lesions.
Shen SW, Yuwen Y, Zhang ZL, Dong S, Liu JT, Wang XM
Chinese journal of integrative medicine 2008 Sep;14(3):212-6
Chinese journal of integrative medicine 2008 Sep;14(3):212-6
P53 transcription-independent activity mediates selenite-induced acute promyelocytic leukemia NB4 cell apoptosis.
Guan L, Huang F, Li Z, Han B, Jiang Q, Ren Y, Yang Y, Xu C
BMB reports 2008 Oct 31;41(10):745-50
BMB reports 2008 Oct 31;41(10):745-50
Telomerase catalyzed fluorescent probes for sensitive protein profiling based on one-dimensional microfluidic beads array.
Wen J, Yang X, Wang K, Tan W, Zuo X, Zhang H
Biosensors & bioelectronics 2008 Jul 15;23(12):1788-92
Biosensors & bioelectronics 2008 Jul 15;23(12):1788-92
Knockdown of survivin and upregulation of p53 gene expression by small interfering RNA induces apoptosis in human gastric carcinoma cell line SGC-823.
Lu YH, Wang K, He R, Xi T
Cancer biotherapy & radiopharmaceuticals 2008 Dec;23(6):727-34
Cancer biotherapy & radiopharmaceuticals 2008 Dec;23(6):727-34
IFITM1 plays an essential role in the antiproliferative action of interferon-gamma.
Yang G, Xu Y, Chen X, Hu G
Oncogene 2007 Jan 25;26(4):594-603
Oncogene 2007 Jan 25;26(4):594-603
Expression of hTERT, p53 and PCNA in cystitis glandularis.
Wei Z, Ye Z, Chen Z
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2007 Aug;27(4):437-9
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2007 Aug;27(4):437-9
Trans-arterial gene therapy for hepatocellular carcinoma in a rabbit model.
Gu T, Li CX, Feng Y, Wang Q, Li CH, Li CF
World journal of gastroenterology : WJG 2007 Apr 14;13(14):2113-7
World journal of gastroenterology : WJG 2007 Apr 14;13(14):2113-7
Expression of Egr-1 gene and its correlation with the oncogene proteins in non-irradiated and irradiated esophageal squamous cell carcinoma.
Wu MY, Wu XY, Li QS, Zheng RM
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E 2006;19(4):267-72
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E 2006;19(4):267-72
Quantitative intracellular molecular profiling using a one-dimensional flow system.
Zhou L, Wang K, Tan W, Chen Y, Zuo X, Wen J, Liu B, Tang H, He L, Yang X
Analytical chemistry 2006 Sep 1;78(17):6246-51
Analytical chemistry 2006 Sep 1;78(17):6246-51
Effects of tachyplesin and n-sodium butyrate on proliferation and gene expression of human gastric adenocarcinoma cell line BGC-823.
Shi SL, Wang YY, Liang Y, Li QF
World journal of gastroenterology : WJG 2006 Mar 21;12(11):1694-8
World journal of gastroenterology : WJG 2006 Mar 21;12(11):1694-8
Expression of BIRC7 protein and mRNA in non-Hodgkin's lymphoma.
Wu H, Ma Y, Zhu Y, Shen Y, Gu C, Ye Z, Lin H
Leukemia & lymphoma 2006 Jun;47(6):1110-6
Leukemia & lymphoma 2006 Jun;47(6):1110-6
Radiosensitivity of human colon cancer cell enhanced by immunoliposomal docetaxel.
Wang QW, Lu HL, Song CC, Liu H, Xu CG
World journal of gastroenterology : WJG 2005 Jul 14;11(26):4003-7
World journal of gastroenterology : WJG 2005 Jul 14;11(26):4003-7
Effects of sulfur dioxide on apoptosis-related gene expressions in lungs from rats.
Bai J, Meng Z
Regulatory toxicology and pharmacology : RTP 2005 Dec;43(3):272-9
Regulatory toxicology and pharmacology : RTP 2005 Dec;43(3):272-9
Expression of apoptosis-related genes in livers from rats exposed to sulfur dioxide.
Bai J, Meng Z
Toxicology 2005 Dec 15;216(2-3):253-60
Toxicology 2005 Dec 15;216(2-3):253-60
Growth-inhibitory effects of curcumin on ovary cancer cells and its mechanisms.
Zheng L, Tong Q, Wu C
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2004;24(1):55-8
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2004;24(1):55-8
Effects of novel safrole oxide derivatives, 1-propyl-3-(3,4-methylenedioxyphenyl)-2-propanol and 1-isopropoxy-3-(3,4-methylenedioxyphenyl)-2-propanol, on apoptosis induced by deprivation of survival factors in vascular endothelial cells.
Zhao J, Zhao B, Du A, Zhao Q, Miao J
Endothelium : journal of endothelial cell research 2004 Sep-Dec;11(5-6):267-73
Endothelium : journal of endothelial cell research 2004 Sep-Dec;11(5-6):267-73
Cytochrome C oxidase III interacts with hepatitis B virus X protein in vivo by yeast two-hybrid system.
Li D, Wang XZ, Yu JP, Chen ZX, Huang YH, Tao QM
World journal of gastroenterology : WJG 2004 Oct 1;10(19):2805-8
World journal of gastroenterology : WJG 2004 Oct 1;10(19):2805-8
Effects of Chinese medicinal fungus water extract on tumor metastasis and some parameters of immune function.
Zhang W, Wang Y, Hou Y
International immunopharmacology 2004 Mar;4(3):461-8
International immunopharmacology 2004 Mar;4(3):461-8
Integrin beta4 mAb inhibited apoptosis induced by deprivation of growth factors in vascular endothelial cells.
Zhao KW, Zhao QT, Zhang SL, Miao JY
Acta pharmacologica Sinica 2004 Jun;25(6):733-7
Acta pharmacologica Sinica 2004 Jun;25(6):733-7
BAK overexpression mediates p53-independent apoptosis inducing effects on human gastric cancer cells.
Tong QS, Zheng LD, Wang L, Liu J, Qian W
BMC cancer 2004 Jul 12;4:33
BMC cancer 2004 Jul 12;4:33
Integrin beta 4 is a target of rattlesnake venom during inducing apoptosis of vascular endothelial cells.
Zhao Q, Wang N, Jia R, Zhang S, Miao J
Vascular pharmacology 2004 Feb;41(1):1-6
Vascular pharmacology 2004 Feb;41(1):1-6
Apoptosis mediated by phosphatidylcholine-specific phospholipase C is associated with cAMP, p53 level, and cell-cycle distribution in vascular endothelial cells.
Du C, Zhao Q, Araki S, Zhang S, Miao J
Endothelium : journal of endothelial cell research 2003;10(3):141-7
Endothelium : journal of endothelial cell research 2003;10(3):141-7
Helicobacter pylori infection generated gastric cancer through p53-Rb tumor-suppressor system mutation and telomerase reactivation.
Lan J, Xiong YY, Lin YX, Wang BC, Gong LL, Xu HS, Guo GS
World journal of gastroenterology : WJG 2003 Jan;9(1):54-8
World journal of gastroenterology : WJG 2003 Jan;9(1):54-8
Study on apoptosis and expression of P53, bcl-2, Bax in cardiac myocytys of congestive heart failure induced by ventricular pacing.
Qi B, Cao L, Wang L, Zhou J
Journal of Tongji Medical University = Tong ji yi ke da xue xue bao 2001;21(3):202-5
Journal of Tongji Medical University = Tong ji yi ke da xue xue bao 2001;21(3):202-5
P21WAF1/Cip1 gene expression in primary human hepatocellular carcinoma and its relationship with P53 gene mutation.
Sun B, Wu Z, Ruan Y, Yang M, Liu B
Journal of Tongji Medical University = Tong ji yi ke da xue xue bao 1999;19(1):1-5
Journal of Tongji Medical University = Tong ji yi ke da xue xue bao 1999;19(1):1-5
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB: HL-60 Cell Lysate
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC(P): Human Mammary Cancer Tissue
