11-8059-25

antibody from ABEOMICS Inc.
Targeting: ARRB1 ARR1
Provider product page for 11-8059-25

Antibody data

Product number
11-8059-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-Beta-arrestin 1 Antibody
Antibody type
Polyclonal
Description
Beta-arrestin 1, a member of arrestin family, is a cofactor of beta-adrenergic receptor kinase (BARK) in beta-adrenergic receptor desensitization and resensitization process. Beta-arrestin 1 acts as endocytic adapter for internalization of many G-protein coupled receptors. Beta-arrestin 1 is also associated with many other cellular processes like ubiquitination and down-regulation of the insulin-like growth factor-1 receptor, synaptic transmission in photoreceptor cells, working as a scaffold protein in G-protein coupled receptor signaling pathways. Two isoforms of beta-arrestin 1 have been identified, isoform 1 (47 kDa) and isoform 2 (46 kDa). Beta-arrestin 1 is highly expressed in liver, kidney, lungs and testes.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant Beta-a
rrestin 1 protein (amino acids 150-
318) was used as the immunogen for
this antibody.
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
ARRB1 protein structure - 11-8059-25 shown in red.