Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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Validation data
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- Product number
- ABIN950521 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Arrestin, beta 1 (ARRB1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Other
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 0.1 mg
Submitted references Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4.
Prostaglandin E2 promotes lung cancer cell migration via EP4-betaArrestin1-c-Src signalsome.
Cross talk between phosphatidylinositol 3-kinase and cyclic AMP (cAMP)-protein kinase a signaling pathways at the level of a protein kinase B/beta-arrestin/cAMP phosphodiesterase 4 complex.
The fate of the internalized apelin receptor is determined by different isoforms of apelin mediating differential interaction with beta-arrestin.
Role of macrophage oxidative burst in the action of anthrax lethal toxin.
Shukla AK, Kim J, Ahn S, Xiao K, Shenoy SK, Liedtke W, Lefkowitz RJ
The Journal of biological chemistry 2010 Sep 24;285(39):30115-25
The Journal of biological chemistry 2010 Sep 24;285(39):30115-25
Prostaglandin E2 promotes lung cancer cell migration via EP4-betaArrestin1-c-Src signalsome.
Kim JI, Lakshmikanthan V, Frilot N, Daaka Y
Molecular cancer research : MCR 2010 Apr;8(4):569-77
Molecular cancer research : MCR 2010 Apr;8(4):569-77
Cross talk between phosphatidylinositol 3-kinase and cyclic AMP (cAMP)-protein kinase a signaling pathways at the level of a protein kinase B/beta-arrestin/cAMP phosphodiesterase 4 complex.
Bjørgo E, Solheim SA, Abrahamsen H, Baillie GS, Brown KM, Berge T, Okkenhaug K, Houslay MD, Taskén K
Molecular and cellular biology 2010 Apr;30(7):1660-72
Molecular and cellular biology 2010 Apr;30(7):1660-72
The fate of the internalized apelin receptor is determined by different isoforms of apelin mediating differential interaction with beta-arrestin.
Lee DK, Ferguson SS, George SR, O'Dowd BF
Biochemical and biophysical research communications 2010 Apr 30;395(2):185-9
Biochemical and biophysical research communications 2010 Apr 30;395(2):185-9
Role of macrophage oxidative burst in the action of anthrax lethal toxin.
Hanna PC, Kruskal BA, Ezekowitz RA, Bloom BR, Collier RJ
Molecular medicine (Cambridge, Mass.) 1994 Nov;1(1):7-18
Molecular medicine (Cambridge, Mass.) 1994 Nov;1(1):7-18
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ARRB1 Antibody (C-term) (Cat. #AP50255PU-N) western blot analysis in A549 cell line lysates (35μg/lane).This demonstrates the ARRB1 antibody detected the ARRB1 protein (arrow).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Confocal immunofluorescent analysis of ARRB1 Antibody (C-term)(Cat#AP50255PU-N) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ARRB1 Antibody (C-term) (Cat. #AP50255PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ARRB1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ARRB1 Antibody (C-term) (Cat. #AP50255PU-N) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.