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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Product number
- 600701 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#600701, RRID:AB_315576
- Product name
- Purified anti-Paxillin
- Antibody type
- Polyclonal
- Antigen
- Full length recombinant protein (human)
- Description
- Paxillin (also known as peroxisomal membrane protein 3) is a cytoplasmic protein with LIM metal-binding repeat homology and LIM domains. There are three isoforms of this protein designated as α, β, γ; approximate molecular weight 68 kD. Paxillin is localized to actin-membrane attachment at sites of cell adhesion to extracellular matrix (focal adhesion). This protein undergoes cell adhesion-dependent tyrosine phosphorylation. Paxillin has been shown to interact with FAK, vinculin, src, Crk, p210BRC / ABL, talin, and integrin-β1. The Poly6007 antibody recognizes human, mouse, and rat paxillin and has shown to be useful for Western blotting.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 50 µl
- Storage
- Upon receipt, store frozen at -20° C.
Submitted references Podosomes are present in a postsynaptic apparatus and participate in its maturation.
RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility.
Proszynski TJ, Gingras J, Valdez G, Krzewski K, Sanes JR
Proceedings of the National Academy of Sciences of the United States of America 2009 Oct 27;106(43):18373-8
Proceedings of the National Academy of Sciences of the United States of America 2009 Oct 27;106(43):18373-8
RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility.
Yao H, Dashner EJ, van Golen CM, van Golen KL
Oncogene 2006 Apr 13;25(16):2285-96
Oncogene 2006 Apr 13;25(16):2285-96
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