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Cell line expression
Protein structure
PRKAA1
Protein kinase AMP-activated catalytic subunit alpha 1AMPKa1
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  MA5-15815 |
5 references | Monoclonal |
WB
ICC
IHC
FC
OA
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| antibodies-online | ABIN969364 |
2 references | Monoclonal |
WB
EL
ICC
IHC
FC
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| Novus Biologicals | NBP2-22127 |
8 references | Monoclonal |
WB
EL
ICC
IHC
FC
|
|
| GeneTex | GTX60403 |
1 references | Monoclonal |
WB
EL
ICC
IHC
FC
|
|
| Proteintech Group | 10929-2-AP |
106 references | Polyclonal |
WB
EL
ICC
IHC
|
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