11-0078-41

antibody from Invitrogen Antibodies
Targeting: CD7 GP40, LEU-9, Tp40, TP41
Provider product page for 11-0078-41

Antibody data

Product number
11-0078-41 - Provider product page
Provider
Invitrogen Antibodies
Product name
Anti-CD7 Monoclonal Antibody (4H9), FITC, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: This 4H9 monoclonal antibody reacts with human CD7 (also known as Leu-9 or gp40), a 40-kDa transmembrane glycoprotein belonging to the immunoglobulin superfamily. This molecule is expressed on peripheral blood T lymphocytes and natural killer cells, as well as on lymphoid and myeloid lineage precursors during adult hematopoiesis. Capable of providing a costimulatory signal and associating with CD3 and CD45, CD7 is involved in T cell activation. CD7 has also been detected on numerous T cell-derived leukemias and lymphomias. In fact, because CD7 expression is greater on CD4+ T cells in classical Hodgkin's lymphoma than in benign reactive lymph adenopathy, this molecule may be used as a diagnostic for Hodgkin's lymphoma. Blocking assays demonstrate that this clone recognizes the same epitope as clone 124-1D1. Applications Reported: This 4H9 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 4H9 antibody has been pre-titrated and tested by flow cytometric analysis on normal human peripheral blood cells. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Conjugate
Green dye
Isotype
IgG
Antibody clone number
4H9
Vial size
25 Tests
Concentration
5 µL/Test
Storage
4° C, store in dark, DO NOT FREEZE!
CD7 protein structure - 11-0078-41 shown in red.