BS1068

CLDN4 antibody from Bioworld Technology, Inc
CPE-R, CPETR, CPETR1, hCPE-R, WBSCR8

Antibody data

Product number
BS1068
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1068, RRID:AB_1663948
Product name
Claudin 4 (P192) polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS1068
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 171-220 of Human Claudin-4.
Description
The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is highly restricted to specfic regions of different tissues and variations of Claudin expression may have an important role in transcellular transport through tight junctions. In rat liver, claudin-3 is uniformly expressed, whereas in the pancreas, claudin-3 is expressed in junctions of the duct epithelia and junctions of acinar cells. Claudin-3 binds the peptide toxin Clostridium perfringens enterotoxin (CPE) at the cell surface via the second extracellular loop of claudin-3. The gene encoding human claudin-3 maps to chromosome 7q11.23.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -