Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
CLDN3
Claudin 3C7orf1, CPE-R2, CPETR2, HRVP1, RVP1
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
| Invitrogen Antibodies |  34-1700 |
190 references | Polyclonal |
WB
EL
ICC
IHC
OA
|
|
| Proteintech Group | 16456-1-AP |
11 references | Polyclonal |
WB
EL
IP
IHC
|
|
| Boster Biological Technology | A04393-5 |
Polyclonal |
WB
EL
ICC
IHC
FC
|
||
| R&D Systems | MAB4620 |
1 references | Monoclonal |
ICC
IHC
FC
|
|
| NSJ Bioreagents | RQ5713 |
Polyclonal |
WB
ICC
IHC
FC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider